Post-traumatic stress and post-traumatic growth in patients with COVID-19 after hospital treatment: sociodemographic, clinical and psychological factors
Abstract
The article presents a study of the factors of post-traumatic stress (PTSD) and post-traumatic growth (PTG) in patients undergoing hospital treatment for coronavirus infection. An analysis of the literature showed that the prevalence of PTSD symptoms in patients who have suffered coronavirus infection varies from 3.8% to 34.5%. At the same time, female sex, severity of symptoms, traumatic experience, stigmatization of patients and lack of social support were noted as risk factors for the development of PTSD. However, post-traumatic growth was more often associated with the presence of support, constructive coping strategies, and positive core beliefs. As part of this work, 67 respondents were examined, who were asked to answer semi-structured interview questions, as well as fill out a number of questionnaires to assess the level of emotional maladaptation. According to the results obtained, 19% of respondents had symptoms of depression of varying degrees, 10% of respondents noted clinically significant indicators of anxiety, 6% of patients reported the presence of critical values of PTSD, while a quarter of patients noted high values of PTD. Analysis of factors showed that women are more likely to have indicators of PTSD and PTD. Also, significant factorы in post-traumatic growth was the severity of lung damage and subjective severity of experience, while the duration of hospitalization, stay in intensive care and time after discharge were not associated with any of the studied indicators. Post-traumatic stress was associated with all indicators of stress: financial and domestic difficulties, lack of social and family support, and fear of complications from the disease. Moreover, post-traumatic growth was primarily associated with constructive coping strategies and the availability of financial support.
About the Authors
A. B. KholmogorovaRussian Federation
A. A. Rakhmanina
Russian Federation
O. D. Pugovkina
Russian Federation
T. A. Avakyan
Russian Federation
N. A. Karchevskaya
Russian Federation
S. S. Petrikov
Russian Federation
References
1. World Health Organization. COVID-19 related reports (2020) – Available at: https://www. who.int/zh/emergencies/diseases/novel-coronavirus-2019 (assessed 1.06.2021).
2. Professional Burnout, Symptoms of Emotional Disorders and Distress among Healthcare Professionals during the COVID-19 Epidemic. Konsul'tativnaya psihologiya i psihoterapiya (Counseling Psychology and Psychotherapy). 2020; 28(2): 8–45. (In Russ.)
3. Kholmogorova A.B., Petrikov S.S., Suroegina A.Yu., Mikita O.Yu., Rakhmanina A.A., Roy A.P. Burnout and its Factors in Healthcare Specialists Involved in Providing Care for Patients with Covid-19 at Different Stages of the Pandemic. Zhurnal im. N.V. Sklifosovskogo «Neotlozhnaya medicinskaya pomoshh`». (Russian Sklifosovsky Journal “Emergency medical care). 2020; 9(3):321-337. doi.org/10.23934/2223-9022-2020-9-3-321-337
4. Huang C., Wang Y., Li X., Ren L., et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395: 497–506. doi: 10.1016/S0140-6736(20)30183-5
5. Cattelan J., Castellano S., Merdji H., Audusseau J., Claude B., Feuillassier L., Cunat S., Astrié M., Aquin C., Buis G., Gehant E., Granier A., Kercha H., Le Guillou C., Martin G., Roulot K., Meziani F., Putois O., Helms J. Psychological effects of remote-only communication among reference persons of ICU patients during COVID-19 pandemic. Journal of intensive care. 2021;9(1):5 doi: 10.1186/s40560-020-00520-w.
6. Rabiee A., Nikayin S., Hashem M., Huang M. et. al. Depressive symptoms after critical illness: a systematic review and meta-analysis. Crit Care Med. 2016; 44:1744-1753. doi: 10.1097/CCM.0000000000001811
7. Smith E., Lee A., Smith J., Thiele A., Zeleznik H., Ohtake P. COVID-19 and Post-intensive Care Syndrome: Community-Based Care for ICU Survivors. Home Health Care Management & Practice. 2021; 33(2):117-124. Doi: 10.1177/1084822320974956
8. Wiertz C.M.H., Vints W.A.J., Maas G.J.C.M., Rasquin S.M.C., van Horn Y.Y., Dremmen M.P.M., Hemmen B., Verbunt J.A. COVID-19: Patient Characteristics in the First Phase of Postintensive Care Rehabilitation. Arch Rehabil Res Clin Transl. 2021;3(2):100-108. doi: 10.1016/j.arrct.2021.100108.
9. Colbenson G., Johnson A., Wilson M.. Post-intensive care syndrome: impact, prevention, and management // Breathe (Sheff). 2019; 15: 98-101. doi: 10.1183/20734735.0013-2019
10. Biehl M., Sese D.. Post-intensive care syndrome and COVID-19 - Implications post pandemic. Cleve Clin J Med. 2020. doi: 10.3949/ccjm.87a.ccc055.
11. Johnson C., Suchyta M., Darowski E., Collar E. et. al. Psychological Sequelae in Family Caregivers of Critically III Intensive Care Unit Patients. A Systematic Review. Ann Am Thorac Soc. 2019; 16:894-909. doi: 10.1513/AnnalsATS.201808-540SR
12. Eddy L. Caring for Patients with COVID-19 and Post-Intensive Care Syndrome. [Электронный ресурс]. – Режим доступа: https://www.hopkinsmedicine.org/news/articles/caring-for-patients-with-covid-19-and-post-intensive-care-syndrome
13. Pompeo-Fargnoli A., Fargnoli A.. The Mental Health Impact of the COVID19 Crisis: The Battle Ahead for Inpatient Survivors.Psychosomatics. 2020; 61:567-568. doi: 10.1016/j.psym.2020.04.001
14. Remsik J., Wilcox J., Babady N., McMillen T., et. al. Inflammatory Leptomeningeal Cytokines Mediate COVID-19 Neurologic Symptoms in Cancer Patients. Cancer Cell. 2021; 39:276-283. doi: 10.1016/j.ccell.2021.01.007
15. Bonsaksen T., Heir T., Schou-Bredal I., Ekeberg Ø., Skogstad L., Grimholt T.K. Post-Traumatic Stress Disorder and Associated Factors during the Early Stage of the COVID-19 Pandemic in Norway. Int J Environ Res Public Health. 2020;17(24):9210. doi: 10.3390/ijerph17249210.
16. Einvik G., Dammen T., Ghanima, W., Heir T., et al. Prevalence and Risk Factors for Post- Traumatic Stress in Hospitalized and Non-Hospitalized COVID-19 Patients. Int. J. Environ. Res. Public Health. 2021; 18:2079. doi: 10.3390/ijerph18042079
17. Khademi M., Vaziri-Harami R., Shams J. Prevalence of Mental Health Problems and Its Associated Factors Among Recovered COVID-19 Patients During the Pandemic: A Single-Center Study. Front Psychiatry. 2021. 12:602244. doi: 10.3389/fpsyt.2021.602244. PMID: 33868043; PMCID: PMC8044784.
18. Chen Y., Huang X., Zhang C., An Y., Liang Y., Yang Y., Liu Z. Prevalence and predictors of posttraumatic stress disorder, depression and anxiety among hospitalized patients with coronavirus disease 2019 in China. BMC Psychiatry. 2021;21(1):80. doi: 10.1186/s12888-021-03076-7.
19. Poyraz BÇ, Poyraz CA, Olgun Y, Gürel Ö, Alkan S, Özdemir YE, Balkan İİ, Karaali R. Psychiatric morbidity and protracted symptoms after COVID-19. Psychiatry Res. 2021;295:113604. doi: 10.1016/j.psychres.2020.113604.
20. Calhoun L., Cann A., Tedeschi R., McMillan J.. A correlational test of the relationship between posttraumatic growth, religion, and cognitive processing. J Trauma Stress. 2000; 13; 521-527. doi: 10.1023/A:1007745627077.
21. Jin Y., Xu J., Liu D. The relationship between post traumatic stress disorder and post traumatic growth: gender differences in PTG and PTSD subgroups. Soc. Psychiatry Psychiatr Epidemiol. 2014; 49: 1903–1910. doi: 10.1007/s00127-014-0865-5
22. Tan J., Andriessen K. The Experiences of Grief and Personal Growth in University Students: A Qualitative Study. Int J Environ Res Public Health. 2021;18(4):1899. doi: 10.3390/ijerph18041899.
23. Ye Z., Chen L, Lin D. The Relationship Between Posttraumatic Stress Disorder Symptoms and Posttraumatic Growth Among HIV-Infected Men Who Have Sex With Men in Beijing, China: The Mediating Roles of Coping Strategies. Front Psychol. 2018; 9:1787. doi: 10.3389/fpsyg.2018.01787.
24. Ma Z., Xia Y., Lin Z. Post-Traumatic Growth Following Exposure to Memorial Reports of the 5.12 Wenchuan Earthquake: The Moderating Roles of Self-Esteem and Long-Term PTSD Symptoms. Int J Environ Res Public Health. 2019;16(18):3239. doi: 10.3390/ijerph16183239
25. Shakespeare-Finch J., Lurie-Beck J. A meta-analytic clarification of the relationship between posttraumatic growth and symptoms of posttraumatic distress disorder. J Anxiety Disord. 2014; 28: 223-9. doi: 10.1016/j.janxdis.2013.10.005
26. Butler L., Blasey C., Garlan W., McCaslin S., et al. Post-traumatic growth following the terrorist attacks of September 11, 2001: cognitive, coping, and trauma symptom predictors in an internet convenience sample. Traumatology. 2005;11:247–267. doi: 10.1177/153476560501100405
27. Sergienko A.I., Kholmogorova A.B. Post-Traumatic Growth and Coping-Strategies of Parents of Children with Disabilities. Konsul'tativnaya psikhologiya i psikhoterapiya (Counseling Psychology and Psychotherapy). 2019; 27(2): 8–26. doi:10.17759/cpp.2019270202. (In Russ.)
28. Yan S., Yang J., Ye M., Chen S., Xie C., Huang J., Liu H. Post-traumatic Growth and Related Influencing Factors in Discharged COVID-19 Patients: A Cross-Sectional Study. Front Psychol. 2021; 12:658307. doi: 10.3389/fpsyg.2021.658307.
29. Vazquez, C., Valiente, C., García, F.E. et al. Post-Traumatic Growth and Stress-Related Responses During the COVID-19 Pandemic in a National Representative Sample: The Role of Positive Core Beliefs About the World and Others. J Happiness Stud. 2021; 22: 2915–2935. https://doi.org/10.1007/s10902-020-00352-3
30. Bruno, F., Vozzo, F., Arcuri, D. et al. The longitudinal association between Perceived Stress, PTSD Symptoms, and Post-Traumatic Growth during the COVID-19 Pandemic: the role of coping strategies and psychological inflexibility. Curr Psychol. 2024; 43: 13871–13886. https://doi.org/10.1007/s12144-022-03502-3
31. Tarabrina N.V. Praktikum po psikhologii posttravmaticheskogo stressa. Saint Peterburg: Piter Publ., 2001. (In Russ.)
32. Tarabrina N.V., Kharlamenkova N.E., Padun M.A., Hazhuev I.S., Bykhovets Yu.V., Dan M.V. Intensivnyj stress v kontekste psihologicheskoj bezopasnosti. Moscow: «Institut psihologii RAN» Publ., 2017. 344 p. (In Russ.)
33. Holland J., Bultz B. The NCCN guideline for distress management: a case for making distress the sixth vital sign. J Natl Compr Canc Netw. 2007; 5(1): 3-7. doi: 10.6004/jnccn.2007.0003
34. Olejnikova I.N., Gens G.P., Sirota N.A. A study of distress women in cancer. Klinicheskaya i medicinskaya psihologiya: issledovaniya, obuchenie, praktika (Clinical and medical psychology: researches, studies, practice). 2014; 3(5):4. Available at: http://medpsy.ru/climp/2014_3_5/article13.php (In Russ.) https://doi.org/10.17759/cpp.2020280202 (In Russ., аbstr. in Engl)
35. Magomed-Eminov M.SH. Deyatel'nostno-smyslovoj podhod k psihologicheskoj transformacii lichnosti. 2009. URL: http://www.psy.msu.ru/science/autoref/doc/magomed-eminov.pdf (accessed 01.06.2021) (In Russ.)
36. Rubinshtejn S. YA. Eksperimental'nye metodiki patopsihologii. Moscow: publ. “Psychotherapy”, 2010. (In Russ.)
37. Alfimova M.V. Semanticheskaya verbal'naya beglost': normativnye dannye i osobennosti vypolneniya zadaniya bol'nymi shizofreniej. Social'naya i klinicheskaya psihiatriya. 2010; 20(3): 20-25. URL: https://cyberleninka.ru/article/n/semanticheskaya-verbalnaya-beglost-normativnye-dannye-i-osobennosti-vypolneniya-zadaniya-bolnymi-shizofreniey (accessed 01.06.2021)
38. Nikolaeva V.V. Psihosomatika: telesnost' i kul'tura: Uchebnoe posobie dlya vuzov» // pod red. Nikolaevoj — M.: Akademicheskij proekt, 2009. – 311 p. (In Russ.)
39. Kholmogorova A.B. Biopsychosocial model as a methodological basis for the study of mental disorders. Social'naya i klinicheskaya psihiatriya – 2002;12(3): 97-104
40. Horn M., Wathelet M., Fovet T., Amad A., Vuotto F., Faure K., Astier T., Noël H., Duhem S., Vaiva G., D'Hondt F., Henry M. Is COVID-19 Associated With Posttraumatic Stress Disorder? J Clin Psychiatry. 2022;82(1):20m13641. doi: 10.4088/JCP.20m13641.
41. De Lorenzo R., Conte C., Lanzani C., Benedetti F., Roveri L., Mazza M.G., Brioni E., Giacalone G., Canti V., Sofia V., D'Amico M., Di Napoli D., Ambrosio A., Scarpellini P., Castagna A., Landoni G., Zangrillo A., Bosi E., Tresoldi M., Ciceri F., Rovere-Querini P. Residual clinical damage after COVID-19: A retrospective and prospective observational cohort study. PLoS One. 2020;15(10):e0239570. doi: 10.1371/journal.pone.0239570
42. Mækelæ, Martin & Reggev, Niv & Dutra, Natalia & Tamayo, Ricardo & Silva-Sobrinho, Reinaldo & Klevjer, Kristoffer & Pfuhl, Gerit. Perceived efficacy of COVID-19 restrictions, reactions and their impact on mental health during the early phase of the outbreak in six countries. Royal Society Open Science. 2020;7: 200644. Doi: 10.1098/rsos.200644.
43. Northfield, E.-L., & Johnston, K. L. “I get by with a little help from my friends”: Posttraumatic growth in the COVID-19 pandemic. Traumatology. 2022; 28(1): 195–201. https://doi.org/10.1037/trm0000321
Review
For citations:
Kholmogorova A.B., Rakhmanina A.A., Pugovkina O.D., Avakyan T.A., Karchevskaya N.A., Petrikov S.S. Post-traumatic stress and post-traumatic growth in patients with COVID-19 after hospital treatment: sociodemographic, clinical and psychological factors. Medical Psychology in Russia. 2024;16(1):11-33. (In Russ.)